La Reina

La Reina is a boss enemy in Slay the Spire 2, entering combat with 400 HP (419 on higher Ascensions).

Its attack pattern runs Starts: Puppet Strings → Me perteneces; then conditional: Arde para mí (if does not have amalgam died) / Despídete de tu cabeza (if has amalgam died); then conditional: Arde para mí (if does not have amalgam died) / Despídete de tu cabeza (if has amalgam died).

Its heaviest attack, Despídete de tu cabeza, deals 3×5 (15 total) damage.