Spire Codex is now on Overwolf. Get the in-game overlay with live card lookups and one-click run uploads. Learn more →Spire Codex is now on Overwolf. Get the in-game overlay with live card lookups and one-click run uploads. Learn more →◆Modifier
Insanity is a run modifier in Slay the Spire 2. Modifiers adjust a run's starting conditions or rules so you can tailor the challenge before the run begins.
They are one of the ways Slay the Spire 2 lets you customize difficulty beyond the Ascension ladder.
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