Spire Codex is now on Overwolf. Get the in-game overlay with live card lookups and one-click run uploads. Learn more →How Neow works in Slay the Spire 2: her full relic pool, the curse exclusion rules, and what community runs say about which offer to take.
Neow is back in Slay the Spire 2, but she doesn't work the way she did in the first game. There are no blessing menus with four options anymore. In STS2 she is one of the eight Ancients, and like every Ancient she puts three relics in front of you: two from her positive pool and one from her curse pool. You take one. That's the whole interaction, and it's still one of the biggest swings in the run.
This guide covers her exact pools, the exclusion rules the game uses to build the offer, and what the community stats say about which relics are actually worth taking. All of it comes from the game files and from the runs players have submitted to Spire Codex.
The game picks the curse option first, then removes anything from the positive pool that would overlap with it. That matters more than it sounds, because several of her relics come in mirrored pairs:
So you never get to choose between the free version and the taxed version of the same effect. Neow makes you pay for the bigger number or settle for the smaller one.
A few positive-pool slots are also coin flips between two relics: [[relic:Lava Rock]] or [[relic:Small Capsule]], [[relic:Neow's Talisman]] or [[relic:Pomander]], [[relic:Nutritious Oyster]] or [[relic:Stone Humidifier]]. And two are situational: [[relic:Massive Scroll]] only shows up in multiplayer, [[relic:Scroll Boxes]] only if your deck can form bundles.
From over 800,000 submitted runs:
The pattern is simple: players pay HP and deck pollution for early rares, and they're right to. Early scaling wins runs in STS2 the same way it did in the first game.
The right pick depends on what your character wants, and STS2's five characters want different things.
If you plan to fight act 1 elites, [[relic:Booming Conch]] (draw 2 extra cards at the start of elite combats) turns those fights from a gamble into a farm. [[relic:Lava Rock]] (the act 1 boss drops 2 relics) is the other elite-adjacent pick, a guaranteed payoff for surviving.
If your deck plan needs thinning, take the removal even when it's taxed. Necrobinder and Silent both come online faster with starters gone, and [[relic:Precarious Shears]]' 16 HP is worth two removals on floor 1 if you route toward an early rest site.
If you're on Defect or Regent and need to hit power spikes, the card relics ([[relic:Hefty Tablet]], [[relic:Arcane Scroll]], [[relic:Kaleidoscope]] for off-character cards) beat the economy relics. Ironclad can afford greedier picks like [[relic:Cursed Pearl]] since gold converts to shop removals anyway.
And don't sleep on [[relic:Phial Holster]]. A potion slot plus two random potions is quiet, but potions carry more fights in STS2 than most players give them credit for.
Two of her relics reference her directly and both are gambles. [[relic:Neow's Torment]] adds [[Neow's Fury]] to your deck, a card you either build around or resent every shuffle. [[relic:Neow's Bones]], from the curse pool, hands you 2 random Neow relics plus a random curse, which is the closest thing STS2 has to the old boss relic swap: sometimes you walk away with [[relic:Fishing Rod]] and [[relic:Winged Boots]], sometimes you get punished.
Take the rare card options unless your HP is already committed elsewhere. Pay for removal if your deck plan needs to be thin. Check whether the curse option locks out the free version of something you wanted, because if the free version is still on the table, the taxed one has to beat it by a lot.
Every relic in this guide links to live win-rate and pick-rate data on its page, and the full offer tables for all eight Ancients are on the Ancients page. If you want to see how your own Neow picks stack up, upload your runs and check the community stats.
View all of the cards and relics so that way you can stay aware of what others are picking and how everyone is climbing the tower. The tier list helps decide what the best players are doing and can help you make more informed decisions.
Written by Spire Codex·Recommend an edit